topotecan (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View topotecan's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
topotecan Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Camptothecin Compound (Entity type)	0.8619877696037292
topotecan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCAND1 Gene (Entity type)	0.015166153
topotecan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDB2 Gene (Entity type)	0.02362716
SIB-1893 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	topotecan Compound (Entity type)	0.649643063545227
idarubicin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	topotecan Compound (Entity type)	0.7601781487464905
Skatole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	topotecan Compound (Entity type)	0.2292077988386154
topotecan Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	DNA topoisomerase 1 Protein (Entity type)	IC50
topotecan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT17 Gene (Entity type)	0.01940039
topotecan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	-0.014963841
topotecan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3BP Gene (Entity type)	0.018518724

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.