9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TAGLN Gene (Entity type)	-0.010115684
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WSB1 Gene (Entity type)	0.010428401
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ACTC1 Gene (Entity type)	-0.009161286
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGA6 Gene (Entity type)	0.010242538
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POSTN Gene (Entity type)	-0.009366786
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCK2 Gene (Entity type)	-0.011132814
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	C14orf132 Gene (Entity type)	-0.00806234
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.013682848
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COMT Gene (Entity type)	-0.008025912
9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL1 Gene (Entity type)	0.016331237

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TAGLN
Gene (Entity type)
-0.010115684

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
WSB1
Gene (Entity type)
0.010428401

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ACTC1
Gene (Entity type)
-0.009161286

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGA6
Gene (Entity type)
0.010242538

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
POSTN
Gene (Entity type)
-0.009366786

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PCK2
Gene (Entity type)
-0.011132814

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
C14orf132
Gene (Entity type)
-0.00806234

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.013682848

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COMT
Gene (Entity type)
-0.008025912

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL1
Gene (Entity type)
0.016331237

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