N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MXI1 Gene (Entity type)	0.028574098
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MECOM Gene (Entity type)	-0.012924669
VU-0418933-1 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	0.8176273703575134
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H2BC5 Gene (Entity type)	-0.01524013
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.042299878
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MGP Gene (Entity type)	-0.014821275
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM45A Gene (Entity type)	0.02744088
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Hypoxia-inducible factor 1-alpha Protein (Entity type)	EC50
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCNF Gene (Entity type)	-0.01733184
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TDO2 Gene (Entity type)	-0.01573759

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MXI1
Gene (Entity type)
0.028574098

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MECOM
Gene (Entity type)
-0.012924669

VU-0418933-1
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
0.8176273703575134

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H2BC5
Gene (Entity type)
-0.01524013

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.042299878

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MGP
Gene (Entity type)
-0.014821275

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM45A
Gene (Entity type)
0.02744088

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Hypoxia-inducible factor 1-alpha
Protein (Entity type)
EC50

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCNF
Gene (Entity type)
-0.01733184

N-(biphenyl-3-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TDO2
Gene (Entity type)
-0.01573759

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