(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AGT Gene (Entity type)	0.010021271
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MBNL2 Gene (Entity type)	-0.015916886
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	0.009606381
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD5438 Compound (Entity type)	0.5219658017158508
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN13 Gene (Entity type)	-0.012309254
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RXYLT1 Gene (Entity type)	0.011982847
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SORL1 Gene (Entity type)	-0.014474241
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PER2 Gene (Entity type)	0.010141563
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase Chk1 Protein (Entity type)	IC50
(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD55 Gene (Entity type)	-0.017603159

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AGT
Gene (Entity type)
0.010021271

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MBNL2
Gene (Entity type)
-0.015916886

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
0.009606381

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
AZD5438
Compound (Entity type)
0.5219658017158508

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN13
Gene (Entity type)
-0.012309254

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RXYLT1
Gene (Entity type)
0.011982847

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SORL1
Gene (Entity type)
-0.014474241

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PER2
Gene (Entity type)
0.010141563

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase Chk1
Protein (Entity type)
IC50

(S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD55
Gene (Entity type)
-0.017603159

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Knowledge Graph Assertions

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