(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HILPDA Gene (Entity type)	0.005682622
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrix metalloproteinase-16 Protein (Entity type)	IC50
AG-494 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	0.3541743457317352
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BNIP3L Gene (Entity type)	0.0060908985
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC2A1 Gene (Entity type)	0.0058326796
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BNIP3 Gene (Entity type)	0.0056950273
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STC2 Gene (Entity type)	0.0052625174
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI2 Gene (Entity type)	-0.0032478126
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLD Gene (Entity type)	-0.004813362
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.0048292195

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HILPDA
Gene (Entity type)
0.005682622

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Matrix metalloproteinase-16
Protein (Entity type)
IC50

AG-494
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
0.3541743457317352

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BNIP3L
Gene (Entity type)
0.0060908985

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC2A1
Gene (Entity type)
0.0058326796

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BNIP3
Gene (Entity type)
0.0056950273

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STC2
Gene (Entity type)
0.0052625174

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TFPI2
Gene (Entity type)
-0.0032478126

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLD
Gene (Entity type)
-0.004813362

(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.0048292195

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