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Bosentan (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Bosentan's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RHOB Gene (Entity type)	-0.004853457
	Bosentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRC Gene (Entity type)	0.004090963
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SRPX2 Gene (Entity type)	-0.0030214181
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCL20 Gene (Entity type)	-0.0046279524
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL3 Gene (Entity type)	-0.003757862
	Bosentan Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Pulmonary Hypertension Disease or Phenotype (Entity type)
	Bosentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CAST Gene (Entity type)	0.0038039503
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AGR2 Gene (Entity type)	-0.004195615
	Bosentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ME1 Gene (Entity type)	-0.003418397
	Bosentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPA4 Gene (Entity type)	0.003185858

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RHOB
Gene (Entity type)
-0.004853457

Bosentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRC
Gene (Entity type)
0.004090963

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SRPX2
Gene (Entity type)
-0.0030214181

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCL20
Gene (Entity type)
-0.0046279524

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL3
Gene (Entity type)
-0.003757862

Bosentan
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Pulmonary Hypertension
Disease or Phenotype (Entity type)

Bosentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CAST
Gene (Entity type)
0.0038039503

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AGR2
Gene (Entity type)
-0.004195615

Bosentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ME1
Gene (Entity type)
-0.003418397

Bosentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPA4
Gene (Entity type)
0.003185858

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