4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAP2 Gene (Entity type)	-0.0056545353
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFIT1 Gene (Entity type)	0.0044112075
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.003902173
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage colony-stimulating factor 1 receptor Protein (Entity type)	IC50
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MEF2C Gene (Entity type)	0.004453417
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GGH Gene (Entity type)	0.0044709444
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline Compound (Entity type)	0.5265305042266846
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DCLK1 Gene (Entity type)	-0.004093092
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPN Gene (Entity type)	0.0040050587
4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MRPS16 Gene (Entity type)	0.004826982

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STAP2
Gene (Entity type)
-0.0056545353

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFIT1
Gene (Entity type)
0.0044112075

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.003902173

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Macrophage colony-stimulating factor 1 receptor
Protein (Entity type)
IC50

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MEF2C
Gene (Entity type)
0.004453417

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GGH
Gene (Entity type)
0.0044709444

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
Compound (Entity type)
0.5265305042266846

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DCLK1
Gene (Entity type)
-0.004093092

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPN
Gene (Entity type)
0.0040050587

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MRPS16
Gene (Entity type)
0.004826982

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.