(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EFEMP1 Gene (Entity type)	0.006177024
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SFTPB Gene (Entity type)	0.007948818
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD81 Gene (Entity type)	0.0063802274
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TF Gene (Entity type)	-0.008065742
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLK10 Gene (Entity type)	-0.011517582
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT14 Gene (Entity type)	-0.017723553
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	CREB-binding protein Protein (Entity type)	IC50
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPR137B Gene (Entity type)	0.0061493404
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TM4SF1 Gene (Entity type)	-0.010327888
(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SFTPC Gene (Entity type)	0.0067156353

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EFEMP1
Gene (Entity type)
0.006177024

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SFTPB
Gene (Entity type)
0.007948818

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD81
Gene (Entity type)
0.0063802274

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TF
Gene (Entity type)
-0.008065742

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLK10
Gene (Entity type)
-0.011517582

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT14
Gene (Entity type)
-0.017723553

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
CREB-binding protein
Protein (Entity type)
IC50

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPR137B
Gene (Entity type)
0.0061493404

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TM4SF1
Gene (Entity type)
-0.010327888

(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SFTPC
Gene (Entity type)
0.0067156353

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