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Amlodipine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Amlodipine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Amlodipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CRYAB Gene (Entity type)	-0.0033175729
	Amlodipine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	0.0042782463
	Amlodipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1E Gene (Entity type)	-0.0030282168
	Amlodipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGAP29 Gene (Entity type)	-0.0029374985
	Amlodipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPING1 Gene (Entity type)	-0.0037364392
	Amlodipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPM6B Gene (Entity type)	-0.0029426995
	Amlodipine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CENPU Gene (Entity type)	0.0035808212
	Amlodipine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GREM1 Gene (Entity type)	0.0036734256
	Amlodipine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Cerebrovascular accident Disease or Phenotype (Entity type)
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Amlodipine Compound (Entity type)	0.3799068629741668

Amlodipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CRYAB
Gene (Entity type)
-0.0033175729

Amlodipine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR24
Gene (Entity type)
0.0042782463

Amlodipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1E
Gene (Entity type)
-0.0030282168

Amlodipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ARHGAP29
Gene (Entity type)
-0.0029374985

Amlodipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPING1
Gene (Entity type)
-0.0037364392

Amlodipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPM6B
Gene (Entity type)
-0.0029426995

Amlodipine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CENPU
Gene (Entity type)
0.0035808212

Amlodipine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GREM1
Gene (Entity type)
0.0036734256

Amlodipine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Cerebrovascular accident
Disease or Phenotype (Entity type)

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Amlodipine
Compound (Entity type)
0.3799068629741668

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