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QX-314 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View QX-314's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	QX-314 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	0.009104215
	QX-314 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.01339597
	QX-314 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	0.3187407255172729
	ST-91 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	QX-314 Compound (Entity type)	0.2537080347537994
	QX-314 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	MW-STK33-1B Compound (Entity type)	0.2569791376590729
	QX-314 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHI3L1 Gene (Entity type)	-0.012458502
	QX-314 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMP3 Gene (Entity type)	-0.009996825
	QX-314 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTPRN2 Gene (Entity type)	-0.010127852
	QX-314 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	-0.011394283
	QX-314 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CANT1 Gene (Entity type)	0.009197256

QX-314
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
0.009104215

QX-314
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.01339597

QX-314
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
0.3187407255172729

ST-91
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
QX-314
Compound (Entity type)
0.2537080347537994

QX-314
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
MW-STK33-1B
Compound (Entity type)
0.2569791376590729

QX-314
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHI3L1
Gene (Entity type)
-0.012458502

QX-314
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMP3
Gene (Entity type)
-0.009996825

QX-314
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PTPRN2
Gene (Entity type)
-0.010127852

QX-314
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
-0.011394283

QX-314
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CANT1
Gene (Entity type)
0.009197256

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