N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRR7 Gene (Entity type)	0.0062445523
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	BMS-345541 Compound (Entity type)	0.4018540382385254
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH3A2 Gene (Entity type)	-0.004974807
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MRPS16 Gene (Entity type)	-0.0057062977
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Focal adhesion kinase 1 Protein (Entity type)	IC50
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CMAHP Gene (Entity type)	-0.004944924
SID103905684 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	0.5870301127433777
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABCA1 Gene (Entity type)	-0.004801609
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3BP Gene (Entity type)	0.0055408836
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLBD1 Gene (Entity type)	0.0051872153

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRR7
Gene (Entity type)
0.0062445523

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
BMS-345541
Compound (Entity type)
0.4018540382385254

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH3A2
Gene (Entity type)
-0.004974807

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MRPS16
Gene (Entity type)
-0.0057062977

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Focal adhesion kinase 1
Protein (Entity type)
IC50

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CMAHP
Gene (Entity type)
-0.004944924

SID103905684
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
0.5870301127433777

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ABCA1
Gene (Entity type)
-0.004801609

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3BP
Gene (Entity type)
0.0055408836

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLBD1
Gene (Entity type)
0.0051872153

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