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linsitinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View linsitinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	linsitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.0031015675
	linsitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.0039595766
	linsitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	-0.003949764
	linsitinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD-2014::CHEMBL2336325::US9102670, 1ap Compound (Entity type)	0.5896919369697571
	linsitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMX4 Gene (Entity type)	0.0040283506
	linsitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABCC3 Gene (Entity type)	0.003753715
	linsitinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Insulin receptor-related protein Protein (Entity type)	IC50
	Purmorphamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	linsitinib Compound (Entity type)	0.3622447550296783
	(R)-5-((2-(3-aminopiperidin-1-yl)biphenyl-3-yl)methylene)thiazolidine-2,4-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	linsitinib Compound (Entity type)	0.3501069545745849
	linsitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA6 Gene (Entity type)	-0.0046813814

linsitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
-0.0031015675

linsitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IER3
Gene (Entity type)
0.0039595766

linsitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
-0.003949764

linsitinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
AZD-2014::CHEMBL2336325::US9102670, 1ap
Compound (Entity type)
0.5896919369697571

linsitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMX4
Gene (Entity type)
0.0040283506

linsitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABCC3
Gene (Entity type)
0.003753715

linsitinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Insulin receptor-related protein
Protein (Entity type)
IC50

Purmorphamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
linsitinib
Compound (Entity type)
0.3622447550296783

(R)-5-((2-(3-aminopiperidin-1-yl)biphenyl-3-yl)methylene)thiazolidine-2,4-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
linsitinib
Compound (Entity type)
0.3501069545745849

linsitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA6
Gene (Entity type)
-0.0046813814

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