tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	0.024396624
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TENT5A Gene (Entity type)	-0.011701355
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TLCD3A Gene (Entity type)	-0.010884949
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STC1 Gene (Entity type)	-0.009159308
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GOT1 Gene (Entity type)	0.0142647335
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.010450412
Ro-28-1675 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	0.6762180924415588
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF2 Gene (Entity type)	0.018671311
3'-fluorobenzylspiperone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	0.5424392223358154
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTGS2 Gene (Entity type)	-0.01053096

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
0.024396624

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TENT5A
Gene (Entity type)
-0.011701355

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TLCD3A
Gene (Entity type)
-0.010884949

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STC1
Gene (Entity type)
-0.009159308

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GOT1
Gene (Entity type)
0.0142647335

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.010450412

Ro-28-1675
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
0.6762180924415588

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARHGEF2
Gene (Entity type)
0.018671311

3'-fluorobenzylspiperone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
0.5424392223358154

tert-butyl 3-[(2S,5S,8S)-2-isobutyl-14-methoxy-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0(3,8.0)11,16]heptadeca-1(10),11,13,15-tetraene-5-yl]propanoate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PTGS2
Gene (Entity type)
-0.01053096

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