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MK-2206 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MK-2206's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.007814262
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.005751703
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	0.00517097
	MK-2206 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPD52L1 Gene (Entity type)	-0.0038752866
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.0056838756
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FDPS Gene (Entity type)	0.005081071
	MK-2206 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOLR1 Gene (Entity type)	-0.0035905703
	JW-7-24-1 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	MK-2206 Compound (Entity type)	0.536669909954071
	MK-2206 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP51A1 Gene (Entity type)	0.0053246543
	MK-2206 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	RAC-gamma serine/threonine-protein kinase Protein (Entity type)	IC50

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.007814262

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.005751703

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
0.00517097

MK-2206
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPD52L1
Gene (Entity type)
-0.0038752866

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.0056838756

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FDPS
Gene (Entity type)
0.005081071

MK-2206
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOLR1
Gene (Entity type)
-0.0035905703

JW-7-24-1
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
MK-2206
Compound (Entity type)
0.536669909954071

MK-2206
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP51A1
Gene (Entity type)
0.0053246543

MK-2206
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
RAC-gamma serine/threonine-protein kinase
Protein (Entity type)
IC50

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