6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proto-oncogene tyrosine-protein kinase receptor Ret Protein (Entity type)	IC50
6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	ALK tyrosine kinase receptor Protein (Entity type)	IC50
6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Insulin-like growth factor 1 receptor Protein (Entity type)	IC50

6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein (Entity type)
IC50

6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
ALK tyrosine kinase receptor
Protein (Entity type)
IC50

6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

6,6-dimethyl-11-oxo-8-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Insulin-like growth factor 1 receptor
Protein (Entity type)
IC50

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