N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK1 Gene (Entity type)	-0.010345032
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	VU-0418946-1 Compound (Entity type)	0.8162042498588562
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Apoptosis regulator Bcl-2 Protein (Entity type)	IC50
ST-057710 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	0.3786192238330841
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAFB Gene (Entity type)	-0.008815856
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.008950591
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NRN1 Gene (Entity type)	0.016282748
AMG-9810 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	0.3306385278701782
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MXI1 Gene (Entity type)	0.017017892
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM45A Gene (Entity type)	0.019114017

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLK1
Gene (Entity type)
-0.010345032

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
VU-0418946-1
Compound (Entity type)
0.8162042498588562

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Apoptosis regulator Bcl-2
Protein (Entity type)
IC50

ST-057710
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
0.3786192238330841

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAFB
Gene (Entity type)
-0.008815856

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYP4B1
Gene (Entity type)
-0.008950591

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NRN1
Gene (Entity type)
0.016282748

AMG-9810
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
0.3306385278701782

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MXI1
Gene (Entity type)
0.017017892

N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM45A
Gene (Entity type)
0.019114017

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