(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLF1 Gene (Entity type)	-0.004544583
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 4 Protein (Entity type)	IC50
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH5A1 Gene (Entity type)	-0.004445903
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPN Gene (Entity type)	0.006033458
carglumic-acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	0.4052850306034088
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CAMK2N1 Gene (Entity type)	-0.0050345412
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRB7 Gene (Entity type)	-0.0055689584
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PADI2 Gene (Entity type)	-0.0053612166
palomid-529 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	0.5743710994720459
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.004186192

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MLF1
Gene (Entity type)
-0.004544583

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 4
Protein (Entity type)
IC50

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH5A1
Gene (Entity type)
-0.004445903

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPN
Gene (Entity type)
0.006033458

carglumic-acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
0.4052850306034088

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CAMK2N1
Gene (Entity type)
-0.0050345412

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRB7
Gene (Entity type)
-0.0055689584

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PADI2
Gene (Entity type)
-0.0053612166

palomid-529
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
0.5743710994720459

(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.004186192

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