(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABHD4 Gene (Entity type)	-0.005404564
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TCL1A Gene (Entity type)	0.0052120606
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	-0.0069949413
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VEGFA Gene (Entity type)	-0.0050943103
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	JNK inhibitor IX Compound (Entity type)	0.4017646610736847
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	-0.0052844533
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYAB Gene (Entity type)	0.0060396674
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UCP2 Gene (Entity type)	-0.0052711237
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A12 Gene (Entity type)	0.006429328
(-)-(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 2 Protein (Entity type)	EC50