4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SAT1 Gene (Entity type)	-0.0065068095
Ricinine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	0.2921449244022369
QX-314 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	0.3187407255172729
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC20 Gene (Entity type)	0.008999857
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPH1 Gene (Entity type)	-0.0066982824
dioxane Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	0.2396014332771301
strychnine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	0.3188718557357788
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Fumonisin-b1 Compound (Entity type)	0.5217483639717102
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LIPG Gene (Entity type)	0.005381149
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	-0.0064800857

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SAT1
Gene (Entity type)
-0.0065068095

Ricinine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
0.2921449244022369

QX-314
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
0.3187407255172729

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC20
Gene (Entity type)
0.008999857

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPH1
Gene (Entity type)
-0.0066982824

dioxane
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
0.2396014332771301

strychnine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
0.3188718557357788

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Fumonisin-b1
Compound (Entity type)
0.5217483639717102

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LIPG
Gene (Entity type)
0.005381149

4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
-0.0064800857

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