(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	phenethyl isothiocyanate Compound (Entity type)	0.4146654307842254
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.0092867445
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mineralocorticoid receptor Protein (Entity type)	Ki
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIMM9 Gene (Entity type)	0.008681147
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STXBP2 Gene (Entity type)	-0.0077686068
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAPTM4B Gene (Entity type)	0.008628919
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1B10 Gene (Entity type)	0.020950394
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.008690338
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPX2 Gene (Entity type)	0.013247836
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOSB Gene (Entity type)	-0.012029365

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
phenethyl isothiocyanate
Compound (Entity type)
0.4146654307842254

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
-0.0092867445

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mineralocorticoid receptor
Protein (Entity type)
Ki

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIMM9
Gene (Entity type)
0.008681147

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STXBP2
Gene (Entity type)
-0.0077686068

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LAPTM4B
Gene (Entity type)
0.008628919

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1B10
Gene (Entity type)
0.020950394

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRPM4
Gene (Entity type)
-0.008690338

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPX2
Gene (Entity type)
0.013247836

(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOSB
Gene (Entity type)
-0.012029365

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