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PP1 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PP1's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	PP1 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proto-oncogene tyrosine-protein kinase receptor Ret Protein (Entity type)	Ki
	PP1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.010704122
	PP1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CKB Gene (Entity type)	-0.007403918
	PP1 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein-tyrosine kinase 6 Protein (Entity type)	Ki
	PP1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OPHN1 Gene (Entity type)	0.007696568
	MC-1293 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PP1 Compound (Entity type)	0.2556600868701935
	Manidipine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PP1 Compound (Entity type)	0.2711133062839508
	PP1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHORDC1 Gene (Entity type)	-0.008044562
	PP1 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one Compound (Entity type)	0.4414834082126617
	PP1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	0.007488898

PP1
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein (Entity type)
Ki

PP1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.010704122

PP1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CKB
Gene (Entity type)
-0.007403918

PP1
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein-tyrosine kinase 6
Protein (Entity type)
Ki

PP1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OPHN1
Gene (Entity type)
0.007696568

MC-1293
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PP1
Compound (Entity type)
0.2556600868701935

Manidipine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PP1
Compound (Entity type)
0.2711133062839508

PP1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHORDC1
Gene (Entity type)
-0.008044562

PP1
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one
Compound (Entity type)
0.4414834082126617

PP1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
0.007488898

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