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cerdulatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View cerdulatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	cerdulatinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	palomid-529 Compound (Entity type)	0.3891634345054626
	cerdulatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.008342905
	cerdulatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	OAS2 Gene (Entity type)	-0.007879698
	cerdulatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF9 Gene (Entity type)	-0.0065875305
	cerdulatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase SYK Protein (Entity type)	IC50
	cerdulatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.0078957975
	cerdulatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK2 Protein (Entity type)	IC50
	cerdulatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COG7 Gene (Entity type)	-0.0064053573
	cerdulatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.0051707006
	cerdulatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLS3 Gene (Entity type)	0.0051331967

cerdulatinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
palomid-529
Compound (Entity type)
0.3891634345054626

cerdulatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.008342905

cerdulatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
OAS2
Gene (Entity type)
-0.007879698

cerdulatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IRF9
Gene (Entity type)
-0.0065875305

cerdulatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase SYK
Protein (Entity type)
IC50

cerdulatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HERC5
Gene (Entity type)
-0.0078957975

cerdulatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK2
Protein (Entity type)
IC50

cerdulatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COG7
Gene (Entity type)
-0.0064053573

cerdulatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
0.0051707006

cerdulatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLS3
Gene (Entity type)
0.0051331967

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