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Dabrafenib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Dabrafenib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Dabrafenib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOPX Gene (Entity type)	-0.006799055
	Dabrafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC7A11 Gene (Entity type)	0.011152627
	Dabrafenib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAG3 Gene (Entity type)	-0.0053945757
	Sorafenib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Dabrafenib Compound (Entity type)	0.6419714093208313
	Dabrafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	0.021519596
	Dabrafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STC2 Gene (Entity type)	0.009057905
	Dabrafenib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPB8 Gene (Entity type)	-0.0055759125
	Dabrafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.013156412
	Dabrafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PYCR1 Gene (Entity type)	0.010385966
	Ro-28-1675 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Dabrafenib Compound (Entity type)	0.5494268536567688

Dabrafenib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOPX
Gene (Entity type)
-0.006799055

Dabrafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC7A11
Gene (Entity type)
0.011152627

Dabrafenib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAG3
Gene (Entity type)
-0.0053945757

Sorafenib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Dabrafenib
Compound (Entity type)
0.6419714093208313

Dabrafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
0.021519596

Dabrafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STC2
Gene (Entity type)
0.009057905

Dabrafenib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPB8
Gene (Entity type)
-0.0055759125

Dabrafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.013156412

Dabrafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PYCR1
Gene (Entity type)
0.010385966

Ro-28-1675
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Dabrafenib
Compound (Entity type)
0.5494268536567688

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