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maprotiline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View maprotiline's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	maprotiline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	0.4518639743328094
	maprotiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.005056548
	maprotiline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.0040916554
	maprotiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSPAN8 Gene (Entity type)	0.004338407
	maprotiline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAN2A1 Gene (Entity type)	-0.0029506525
	maprotiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AK4 Gene (Entity type)	0.0033663185
	maprotiline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2C Protein (Entity type)	Ki
	maprotiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SAMSN1 Gene (Entity type)	0.0032898095
	maprotiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP1R3C Gene (Entity type)	0.003333108
	maprotiline Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Mixed anxiety and depressive disorder Disease or Phenotype (Entity type)

maprotiline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
0.4518639743328094

maprotiline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.005056548

maprotiline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.0040916554

maprotiline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSPAN8
Gene (Entity type)
0.004338407

maprotiline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAN2A1
Gene (Entity type)
-0.0029506525

maprotiline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AK4
Gene (Entity type)
0.0033663185

maprotiline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 2C
Protein (Entity type)
Ki

maprotiline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SAMSN1
Gene (Entity type)
0.0032898095

maprotiline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP1R3C
Gene (Entity type)
0.003333108

maprotiline
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Mixed anxiety and depressive disorder
Disease or Phenotype (Entity type)

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