8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	nitrocaramiphen Compound (Entity type)	0.3456180095672607
PG-9 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	0.2255618125200271
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.009545306
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAAT3 Gene (Entity type)	0.00814482
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFITM2 Gene (Entity type)	0.008650331
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCGB2A2 Gene (Entity type)	0.009463616
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD300A Gene (Entity type)	0.008975046
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC5A6 Gene (Entity type)	0.008523185
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFITM1 Gene (Entity type)	0.009962302
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAN2 Gene (Entity type)	-0.008887062

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
nitrocaramiphen
Compound (Entity type)
0.3456180095672607

PG-9
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
0.2255618125200271

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
-0.009545306

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAAT3
Gene (Entity type)
0.00814482

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFITM2
Gene (Entity type)
0.008650331

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCGB2A2
Gene (Entity type)
0.009463616

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD300A
Gene (Entity type)
0.008975046

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC5A6
Gene (Entity type)
0.008523185

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFITM1
Gene (Entity type)
0.009962302

8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PAN2
Gene (Entity type)
-0.008887062

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