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AT-7519 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AT-7519's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	AT-7519 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-dependent kinase 18 Protein (Entity type)	Kd
	AT-7519 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.005411853
	AT-7519 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	-0.005182553
	AT-7519 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SUV39H1 Gene (Entity type)	-0.0054817228
	AT-7519 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FAM171A1 Gene (Entity type)	0.006031651
	AT-7519 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DEFA4 Gene (Entity type)	0.0056783566
	AT-7519 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GUCY1A1 Gene (Entity type)	0.005930093
	AT-7519 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.0059581846
	AT-7519 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ENPP2 Gene (Entity type)	0.0054650325
	AT-7519 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	BMS-387032/SNS-032 Compound (Entity type)	0.6768212914466858

AT-7519
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cyclin-dependent kinase 18
Protein (Entity type)
Kd

AT-7519
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.005411853

AT-7519
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
-0.005182553

AT-7519
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SUV39H1
Gene (Entity type)
-0.0054817228

AT-7519
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FAM171A1
Gene (Entity type)
0.006031651

AT-7519
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DEFA4
Gene (Entity type)
0.0056783566

AT-7519
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GUCY1A1
Gene (Entity type)
0.005930093

AT-7519
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.0059581846

AT-7519
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ENPP2
Gene (Entity type)
0.0054650325

AT-7519
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
BMS-387032/SNS-032
Compound (Entity type)
0.6768212914466858

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