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Nortriptyline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Nortriptyline's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Nortriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKAR2B Gene (Entity type)	-0.0037257357
	Nortriptyline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2B Protein (Entity type)	Ki
	Nortriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKAP12 Gene (Entity type)	-0.0035602073
	Nortriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OLFM4 Gene (Entity type)	0.0037285225
	Nortriptyline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2D6 Protein (Entity type)	IC50
	Nortriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.004148334
	Nortriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CEACAM6 Gene (Entity type)	0.006097181
	Nortriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CAPG Gene (Entity type)	0.004042705
	Nortriptyline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11110785 Compound (Entity type)	0.4681920111179352
	Nortriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ECM1 Gene (Entity type)	0.0038326767

Nortriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKAR2B
Gene (Entity type)
-0.0037257357

Nortriptyline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 2B
Protein (Entity type)
Ki

Nortriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKAP12
Gene (Entity type)
-0.0035602073

Nortriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OLFM4
Gene (Entity type)
0.0037285225

Nortriptyline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2D6
Protein (Entity type)
IC50

Nortriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
-0.004148334

Nortriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CEACAM6
Gene (Entity type)
0.006097181

Nortriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CAPG
Gene (Entity type)
0.004042705

Nortriptyline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID11110785
Compound (Entity type)
0.4681920111179352

Nortriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ECM1
Gene (Entity type)
0.0038326767

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