(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Myosin light chain kinase, smooth muscle Protein (Entity type)	Ki
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	High affinity nerve growth factor receptor Protein (Entity type)	IC50
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase kinase kinase 9 Protein (Entity type)	IC50
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase kinase kinase 11 Protein (Entity type)	IC50
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Calcium/calmodulin-dependent protein kinase kinase 2 Protein (Entity type)	Ki

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Myosin light chain kinase, smooth muscle
Protein (Entity type)
Ki

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
High affinity nerve growth factor receptor
Protein (Entity type)
IC50

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase kinase kinase 9
Protein (Entity type)
IC50

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase kinase kinase 11
Protein (Entity type)
IC50

(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-meth yl-1-oxo-9,12-epoxy-1H diindolo[1,2,3-fg:3',2',1'-kl]py rrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Calcium/calmodulin-dependent protein kinase kinase 2
Protein (Entity type)
Ki

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.