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WZ4002 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View WZ4002's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	WZ4002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP10 Gene (Entity type)	-0.0032086945
	WZ4002 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KEAP1 Gene (Entity type)	0.0024272287
	WZ4002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHI3L1 Gene (Entity type)	-0.0036698955
	Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	WZ4002 Compound (Entity type)	0.3475830554962158
	WZ4002 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	0.0030615453
	WZ4002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	-0.0035621696
	WZ4002 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	NUAK family SNF1-like kinase 1 Protein (Entity type)	Kd
	WZ4002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1F Gene (Entity type)	-0.002787257
	WZ4002 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	0.0027582708
	WZ4002 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Blk Protein (Entity type)	Kd

WZ4002
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CASP10
Gene (Entity type)
-0.0032086945

WZ4002
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KEAP1
Gene (Entity type)
0.0024272287

WZ4002
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHI3L1
Gene (Entity type)
-0.0036698955

Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
WZ4002
Compound (Entity type)
0.3475830554962158

WZ4002
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
0.0030615453

WZ4002
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
-0.0035621696

WZ4002
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
NUAK family SNF1-like kinase 1
Protein (Entity type)
Kd

WZ4002
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1F
Gene (Entity type)
-0.002787257

WZ4002
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
0.0027582708

WZ4002
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Blk
Protein (Entity type)
Kd

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