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clozapine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View clozapine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	clozapine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-2B adrenergic receptor Protein (Entity type)	Ki
	clozapine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	-0.0043444326
	clozapine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS1 Gene (Entity type)	-0.0043358468
	clozapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	0.0042615207
	clozapine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TARBP1 Gene (Entity type)	-0.0041866093
	SID11112285 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	clozapine Compound (Entity type)	0.3015597760677337
	clozapine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC1A1 Gene (Entity type)	-0.0040355413
	clozapine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 3A Protein (Entity type)	Ki
	clozapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC20 Gene (Entity type)	0.0045897732
	estramustine-phosphate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	clozapine Compound (Entity type)	0.4919212758541107

clozapine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-2B adrenergic receptor
Protein (Entity type)
Ki

clozapine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
-0.0043444326

clozapine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS1
Gene (Entity type)
-0.0043358468

clozapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
0.0042615207

clozapine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TARBP1
Gene (Entity type)
-0.0041866093

SID11112285
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
clozapine
Compound (Entity type)
0.3015597760677337

clozapine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC1A1
Gene (Entity type)
-0.0040355413

clozapine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 3A
Protein (Entity type)
Ki

clozapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC20
Gene (Entity type)
0.0045897732

estramustine-phosphate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
clozapine
Compound (Entity type)
0.4919212758541107

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