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BMS-345541 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BMS-345541's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	BMS-345541 Compound (Entity type)	0.4018540382385254
	BMS-345541 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.0069328086
	BMS-345541 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FASTKD5 Gene (Entity type)	0.009329195
	BMS-345541 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	JAG1 Gene (Entity type)	0.0076883445
	BMS-345541 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EMP1 Gene (Entity type)	0.0061766915
	BMS-345541 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	-0.0071825385
	BMS-345541 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CBX5 Gene (Entity type)	-0.004820968
	VU-0420364-1 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	BMS-345541 Compound (Entity type)	0.3700996339321136
	BMS-345541 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NUPR1 Gene (Entity type)	-0.0060052425
	BMS-345541 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Inhibitor of nuclear factor kappa-B kinase subunit alpha Protein (Entity type)	IC50

N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
BMS-345541
Compound (Entity type)
0.4018540382385254

BMS-345541
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.0069328086

BMS-345541
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FASTKD5
Gene (Entity type)
0.009329195

BMS-345541
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
JAG1
Gene (Entity type)
0.0076883445

BMS-345541
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EMP1
Gene (Entity type)
0.0061766915

BMS-345541
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
-0.0071825385

BMS-345541
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CBX5
Gene (Entity type)
-0.004820968

VU-0420364-1
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
BMS-345541
Compound (Entity type)
0.3700996339321136

BMS-345541
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NUPR1
Gene (Entity type)
-0.0060052425

BMS-345541
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Inhibitor of nuclear factor kappa-B kinase subunit alpha
Protein (Entity type)
IC50

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