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Obatoclax (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Obatoclax's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)naphthalene-2-carboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Obatoclax Compound (Entity type)	0.5574653744697571
	Obatoclax Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ACTA2 Gene (Entity type)	-0.01168567
	Obatoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.025242591
	Obatoclax Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID3 Gene (Entity type)	-0.01237727
	Obatoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HERPUD1 Gene (Entity type)	0.020451484
	Pimozide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Obatoclax Compound (Entity type)	0.477282851934433
	N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Obatoclax Compound (Entity type)	0.4954232573509216
	Obatoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.03039573
	Obatoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPC1 Gene (Entity type)	0.02017514
	Obatoclax Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MGP Gene (Entity type)	-0.012041753

(S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)naphthalene-2-carboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Obatoclax
Compound (Entity type)
0.5574653744697571

Obatoclax
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ACTA2
Gene (Entity type)
-0.01168567

Obatoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.025242591

Obatoclax
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID3
Gene (Entity type)
-0.01237727

Obatoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HERPUD1
Gene (Entity type)
0.020451484

Pimozide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Obatoclax
Compound (Entity type)
0.477282851934433

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Obatoclax
Compound (Entity type)
0.4954232573509216

Obatoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
0.03039573

Obatoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPC1
Gene (Entity type)
0.02017514

Obatoclax
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MGP
Gene (Entity type)
-0.012041753

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