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Naltrexone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Naltrexone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Naltrexone Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Therapeutic opioid induced constipation Disease or Phenotype (Entity type)
	Naltrexone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A12 Gene (Entity type)	-0.0056879357
	Naltrexone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT23 Gene (Entity type)	-0.004750782
	Naltrexone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	-0.004571183
	Naltrexone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.0046811365
	Naltrexone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POSTN Gene (Entity type)	0.005054373
	VU-0403126 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Naltrexone Compound (Entity type)	0.2784607708454132
	Naltrexone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CALR Gene (Entity type)	0.0038967999
	Naltrexone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLXNB2 Gene (Entity type)	0.003962158
	Naltrexone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINE2 Gene (Entity type)	-0.004765728

Naltrexone
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Therapeutic opioid induced constipation
Disease or Phenotype (Entity type)

Naltrexone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A12
Gene (Entity type)
-0.0056879357

Naltrexone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT23
Gene (Entity type)
-0.004750782

Naltrexone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
-0.004571183

Naltrexone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.0046811365

Naltrexone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
POSTN
Gene (Entity type)
0.005054373

VU-0403126
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Naltrexone
Compound (Entity type)
0.2784607708454132

Naltrexone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CALR
Gene (Entity type)
0.0038967999

Naltrexone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLXNB2
Gene (Entity type)
0.003962158

Naltrexone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINE2
Gene (Entity type)
-0.004765728

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