2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase ICK Protein (Entity type)	Kd
Chromomycin-a3 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	0.730431318283081
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCNA Gene (Entity type)	-0.009129056
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEL1L3 Gene (Entity type)	0.00574678
JNK-9L Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	0.6360251307487488
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRTAP Gene (Entity type)	0.0058969357
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC39A8 Gene (Entity type)	0.0064303484
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH5A1 Gene (Entity type)	0.00800881
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CALML5 Gene (Entity type)	-0.007938667
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-dependent kinase 9 Protein (Entity type)	Ki

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase ICK
Protein (Entity type)
Kd

Chromomycin-a3
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
0.730431318283081

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PCNA
Gene (Entity type)
-0.009129056

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEL1L3
Gene (Entity type)
0.00574678

JNK-9L
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
0.6360251307487488

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRTAP
Gene (Entity type)
0.0058969357

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC39A8
Gene (Entity type)
0.0064303484

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH5A1
Gene (Entity type)
0.00800881

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CALML5
Gene (Entity type)
-0.007938667

2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cyclin-dependent kinase 9
Protein (Entity type)
Ki

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