8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	-0.009786483
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	-0.010631711
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Rhinorrhea Disease or Phenotype (Entity type)
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM176B Gene (Entity type)	0.0124301
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SVIL Gene (Entity type)	-0.01318148
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Chronic Spontaneous Urticaria Disease or Phenotype (Entity type)
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AGR2 Gene (Entity type)	0.012947869
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Rhinitis, Vasomotor Disease or Phenotype (Entity type)
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	NNC55-0396 Compound (Entity type)	0.2922259867191314
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1G Gene (Entity type)	-0.009459041

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
-0.009786483

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH1A3
Gene (Entity type)
-0.010631711

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Rhinorrhea
Disease or Phenotype (Entity type)

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM176B
Gene (Entity type)
0.0124301

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SVIL
Gene (Entity type)
-0.01318148

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Chronic Spontaneous Urticaria
Disease or Phenotype (Entity type)

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AGR2
Gene (Entity type)
0.012947869

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Rhinitis, Vasomotor
Disease or Phenotype (Entity type)

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
NNC55-0396
Compound (Entity type)
0.2922259867191314

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1G
Gene (Entity type)
-0.009459041

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Knowledge Graph Assertions

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