Zileuton (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Zileuton's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Zileuton Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL10 Gene (Entity type)	0.0042451704
Zileuton Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 Protein (Entity type)	IC50
Zileuton Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLE2 Gene (Entity type)	0.0048941527
Zileuton Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPRY1 Gene (Entity type)	0.004029813
Zileuton Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL9 Gene (Entity type)	0.0043837805
Zileuton Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NAMPT Gene (Entity type)	-0.0041173734
Zileuton Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	JUND Gene (Entity type)	-0.0045668394
Zileuton Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	-0.0037974105
Zileuton Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	-0.0046397005
Zileuton Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Asthma management Disease or Phenotype (Entity type)

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.