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avagacestat (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View avagacestat's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYBG1 Gene (Entity type)	0.0036839442
	avagacestat Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Presenilin-1 Protein (Entity type)	IC50
	avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EREG Gene (Entity type)	-0.005342155
	avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARNT2 Gene (Entity type)	0.0041468213
	avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.004725898
	avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSTA Gene (Entity type)	-0.0047367048
	avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	C2CD5 Gene (Entity type)	0.0038251665
	avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.0041105277
	avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GBP1 Gene (Entity type)	0.0041579884
	avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	0.004355193

avagacestat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRYBG1
Gene (Entity type)
0.0036839442

avagacestat
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Presenilin-1
Protein (Entity type)
IC50

avagacestat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EREG
Gene (Entity type)
-0.005342155

avagacestat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARNT2
Gene (Entity type)
0.0041468213

avagacestat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
-0.004725898

avagacestat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CSTA
Gene (Entity type)
-0.0047367048

avagacestat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
C2CD5
Gene (Entity type)
0.0038251665

avagacestat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
-0.0041105277

avagacestat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GBP1
Gene (Entity type)
0.0041579884

avagacestat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
0.004355193

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