avagacestat (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View avagacestat's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYBG1 Gene (Entity type)	0.0036839442
avagacestat Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Presenilin-1 Protein (Entity type)	IC50
avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EREG Gene (Entity type)	-0.005342155
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARNT2 Gene (Entity type)	0.0041468213
avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.004725898
avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSTA Gene (Entity type)	-0.0047367048
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	C2CD5 Gene (Entity type)	0.0038251665
avagacestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.0041105277
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GBP1 Gene (Entity type)	0.0041579884
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	0.004355193

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.