1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	-0.009977327
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.00949076
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	-0.014046374
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD17B11 Gene (Entity type)	0.010938469
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	-0.011914364
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	0.7265859842300415
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKAP12 Gene (Entity type)	-0.0101759685
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBP1 Gene (Entity type)	0.012169951
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.012536856
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RNMT Gene (Entity type)	0.009070892

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
-0.009977327

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.00949076

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHCR24
Gene (Entity type)
-0.014046374

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSD17B11
Gene (Entity type)
0.010938469

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
-0.011914364

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
0.7265859842300415

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKAP12
Gene (Entity type)
-0.0101759685

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBP1
Gene (Entity type)
0.012169951

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.012536856

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RNMT
Gene (Entity type)
0.009070892

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