4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPTX2 Gene (Entity type)	0.0042739105
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Collagenase 3 Protein (Entity type)	IC50
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAMBI Gene (Entity type)	-0.0043768613
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PF-03084014 Compound (Entity type)	0.4450300335884094
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPA2 Gene (Entity type)	0.003689396
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC45 Gene (Entity type)	0.0036183712
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	-0.0051805587
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID3 Gene (Entity type)	-0.0046700193
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FBP1 Gene (Entity type)	-0.0036940996
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF40 Gene (Entity type)	0.003413526

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPTX2
Gene (Entity type)
0.0042739105

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Collagenase 3
Protein (Entity type)
IC50

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAMBI
Gene (Entity type)
-0.0043768613

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PF-03084014
Compound (Entity type)
0.4450300335884094

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IMPA2
Gene (Entity type)
0.003689396

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC45
Gene (Entity type)
0.0036183712

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP12
Gene (Entity type)
-0.0051805587

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID3
Gene (Entity type)
-0.0046700193

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FBP1
Gene (Entity type)
-0.0036940996

4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARHGEF40
Gene (Entity type)
0.003413526

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