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hydroxyurea (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View hydroxyurea's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PROM1 Gene (Entity type)	-0.004288848
	hydroxyurea Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Malignant neoplasm of ovary Disease or Phenotype (Entity type)
	hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSC22D1 Gene (Entity type)	-0.0031849043
	hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C1 Gene (Entity type)	0.00321137
	hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GDF15 Gene (Entity type)	-0.0035651766
	hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TXNDC9 Gene (Entity type)	0.003178038
	hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLS3 Gene (Entity type)	0.00328388
	hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBE2E3 Gene (Entity type)	0.003198576
	hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAOA Gene (Entity type)	-0.0033123218
	hydroxyurea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribonucleoside-diphosphate reductase subunit M2 Protein (Entity type)	IC50

hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PROM1
Gene (Entity type)
-0.004288848

hydroxyurea
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Malignant neoplasm of ovary
Disease or Phenotype (Entity type)

hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSC22D1
Gene (Entity type)
-0.0031849043

hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C1
Gene (Entity type)
0.00321137

hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GDF15
Gene (Entity type)
-0.0035651766

hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TXNDC9
Gene (Entity type)
0.003178038

hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLS3
Gene (Entity type)
0.00328388

hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBE2E3
Gene (Entity type)
0.003198576

hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAOA
Gene (Entity type)
-0.0033123218

hydroxyurea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribonucleoside-diphosphate reductase subunit M2
Protein (Entity type)
IC50

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