N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLK5 Gene (Entity type)	-0.010041373
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.010869191
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TOB1 Gene (Entity type)	0.008920604
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FMO2 Gene (Entity type)	-0.0069775213
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	WZ-3146 Compound (Entity type)	0.2587483525276184
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADIRF Gene (Entity type)	0.007831591
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D1 Gene (Entity type)	0.007594966
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Polyunsaturated fatty acid 5-lipoxygenase Protein (Entity type)	IC50
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CALML5 Gene (Entity type)	-0.007464998
N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1B10 Gene (Entity type)	0.0105735725

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLK5
Gene (Entity type)
-0.010041373

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.010869191

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TOB1
Gene (Entity type)
0.008920604

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FMO2
Gene (Entity type)
-0.0069775213

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
WZ-3146
Compound (Entity type)
0.2587483525276184

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADIRF
Gene (Entity type)
0.007831591

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSC22D1
Gene (Entity type)
0.007594966

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Polyunsaturated fatty acid 5-lipoxygenase
Protein (Entity type)
IC50

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CALML5
Gene (Entity type)
-0.007464998

N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1B10
Gene (Entity type)
0.0105735725

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.