7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NRIP3 Gene (Entity type)	0.0038300566
piketoprofen Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	0.267500102519989
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDH2 Gene (Entity type)	0.0039687008
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.004124274
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLPH Gene (Entity type)	-0.004212059
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	0.004112359
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)::2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol::CHEMBL608::DH-581::Lorelco::PROBUCOL::US9182402, 14 Compound (Entity type)	0.4158764183521271
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 7 Protein (Entity type)	Ki
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEMA3C Gene (Entity type)	-0.0043203407
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MELK Gene (Entity type)	0.0039059764