Donepezil (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Donepezil's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Donepezil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZIC1 Gene (Entity type)	0.002921617
Donepezil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABLIM1 Gene (Entity type)	0.002856201
Donepezil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GLUL Gene (Entity type)	0.003209558
Donepezil Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Alzheimer's Disease Disease or Phenotype (Entity type)
Donepezil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STK10 Gene (Entity type)	-0.0036019066
Donepezil Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-secretase 1 Protein (Entity type)	IC50
Donepezil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOXB6 Gene (Entity type)	-0.0026445533
Donepezil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT8 Gene (Entity type)	-0.0033420552
Donepezil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RGCC Gene (Entity type)	0.0038698812
Donepezil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OXA1L Gene (Entity type)	0.0030609532

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.