Abemaciclib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Abemaciclib's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD5438 Compound (Entity type)	0.6361256837844849
Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one Compound (Entity type)	0.5137951970100403
Abemaciclib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CENPU Gene (Entity type)	-0.016004492
Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRAK1 Gene (Entity type)	0.011593604
Abemaciclib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-dependent kinase 6 Protein (Entity type)	IC50
momelotinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Abemaciclib Compound (Entity type)	0.4563415050506592
Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ANXA4 Gene (Entity type)	0.012585924
Abemaciclib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.016182357
Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID103905231 Compound (Entity type)	0.5419560074806213
Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACOX2 Gene (Entity type)	0.014561885

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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