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Abemaciclib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Abemaciclib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD5438 Compound (Entity type)	0.6361256837844849
	Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one Compound (Entity type)	0.5137951970100403
	Abemaciclib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CENPU Gene (Entity type)	-0.016004492
	Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRAK1 Gene (Entity type)	0.011593604
	Abemaciclib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-dependent kinase 6 Protein (Entity type)	IC50
	momelotinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Abemaciclib Compound (Entity type)	0.4563415050506592
	Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ANXA4 Gene (Entity type)	0.012585924
	Abemaciclib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.016182357
	Abemaciclib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID103905231 Compound (Entity type)	0.5419560074806213
	Abemaciclib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACOX2 Gene (Entity type)	0.014561885

Abemaciclib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
AZD5438
Compound (Entity type)
0.6361256837844849

Abemaciclib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one
Compound (Entity type)
0.5137951970100403

Abemaciclib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CENPU
Gene (Entity type)
-0.016004492

Abemaciclib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRAK1
Gene (Entity type)
0.011593604

Abemaciclib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cyclin-dependent kinase 6
Protein (Entity type)
IC50

momelotinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Abemaciclib
Compound (Entity type)
0.4563415050506592

Abemaciclib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ANXA4
Gene (Entity type)
0.012585924

Abemaciclib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HPGD
Gene (Entity type)
-0.016182357

Abemaciclib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID103905231
Compound (Entity type)
0.5419560074806213

Abemaciclib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACOX2
Gene (Entity type)
0.014561885

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