[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	meclizine Compound (Entity type)	0.3257681131362915
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPF4 Gene (Entity type)	0.0032243605
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.0028291438
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DOK5 Gene (Entity type)	-0.00271967
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	E2F2 Gene (Entity type)	-0.0042808936
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	0.003262991
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NETO2 Gene (Entity type)	0.002783787
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	tanzisertib Compound (Entity type)	0.3597790002822876
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	JAG1 Gene (Entity type)	-0.0025839547
[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	C7 Gene (Entity type)	0.004737352

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
meclizine
Compound (Entity type)
0.3257681131362915

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPF4
Gene (Entity type)
0.0032243605

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.0028291438

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DOK5
Gene (Entity type)
-0.00271967

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
E2F2
Gene (Entity type)
-0.0042808936

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
0.003262991

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NETO2
Gene (Entity type)
0.002783787

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
tanzisertib
Compound (Entity type)
0.3597790002822876

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
JAG1
Gene (Entity type)
-0.0025839547

[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
C7
Gene (Entity type)
0.004737352

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