(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
maprotiline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	0.4518639743328094
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PABPC4 Gene (Entity type)	-0.0034253136
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EBP Gene (Entity type)	0.0065172235
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGA3 Gene (Entity type)	-0.003283629
SID103905568 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	0.5709817409515381
GSK-1904529A Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	0.3026091456413269
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Epithelial discoidin domain-containing receptor 1 Protein (Entity type)	Kd
AM-92016 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	0.2961114346981048
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACAT2 Gene (Entity type)	0.009224098
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CAV1 Gene (Entity type)	-0.0035198047

maprotiline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
0.4518639743328094

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PABPC4
Gene (Entity type)
-0.0034253136

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EBP
Gene (Entity type)
0.0065172235

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGA3
Gene (Entity type)
-0.003283629

SID103905568
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
0.5709817409515381

GSK-1904529A
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
0.3026091456413269

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Epithelial discoidin domain-containing receptor 1
Protein (Entity type)
Kd

AM-92016
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
0.2961114346981048

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACAT2
Gene (Entity type)
0.009224098

(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CAV1
Gene (Entity type)
-0.0035198047

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Knowledge Graph Assertions

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