2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCK1 Gene (Entity type)	0.020799035
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MGLL Gene (Entity type)	0.0344164
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AHNAK2 Gene (Entity type)	0.0221691
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.022886304
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHRS2 Gene (Entity type)	-0.025801286
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine Compound (Entity type)	0.4707957804203033
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCDC86 Gene (Entity type)	-0.040192198
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1C1 Gene (Entity type)	-0.024832757
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TF Gene (Entity type)	-0.025133805
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC42EP3 Gene (Entity type)	0.024452837

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCK1
Gene (Entity type)
0.020799035

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MGLL
Gene (Entity type)
0.0344164

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AHNAK2
Gene (Entity type)
0.0221691

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APBB2
Gene (Entity type)
-0.022886304

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHRS2
Gene (Entity type)
-0.025801286

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
Compound (Entity type)
0.4707957804203033

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCDC86
Gene (Entity type)
-0.040192198

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1C1
Gene (Entity type)
-0.024832757

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TF
Gene (Entity type)
-0.025133805

2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC42EP3
Gene (Entity type)
0.024452837

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Knowledge Graph Assertions

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