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CHIR-99021 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CHIR-99021's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	CHIR-99021 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CITED2 Gene (Entity type)	-0.009330436
	CHIR-99021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.0072095613
	CHIR-99021 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	KIN001-043 Compound (Entity type)	0.603913426399231
	CHIR-99021 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBP1 Gene (Entity type)	-0.010385114
	CHIR-99021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFRD2 Gene (Entity type)	0.007344514
	CHIR-99021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BHLHE40 Gene (Entity type)	0.009041012
	CHIR-99021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCDC86 Gene (Entity type)	0.00818415
	CHIR-99021 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1G Gene (Entity type)	-0.008136166
	CHIR-99021 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BNIP3L Gene (Entity type)	-0.010537933
	3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CHIR-99021 Compound (Entity type)	0.581808865070343

CHIR-99021
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CITED2
Gene (Entity type)
-0.009330436

CHIR-99021
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.0072095613

CHIR-99021
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
KIN001-043
Compound (Entity type)
0.603913426399231

CHIR-99021
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBP1
Gene (Entity type)
-0.010385114

CHIR-99021
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFRD2
Gene (Entity type)
0.007344514

CHIR-99021
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BHLHE40
Gene (Entity type)
0.009041012

CHIR-99021
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCDC86
Gene (Entity type)
0.00818415

CHIR-99021
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1G
Gene (Entity type)
-0.008136166

CHIR-99021
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BNIP3L
Gene (Entity type)
-0.010537933

3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CHIR-99021
Compound (Entity type)
0.581808865070343

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