3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)'s neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT2A Gene (Entity type)	-0.007485722
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	trimetozine Compound (Entity type)	0.2679053544998169
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD55 Gene (Entity type)	-0.0058578863
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT14 Gene (Entity type)	0.0075287786
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CEACAM5 Gene (Entity type)	0.0063072625
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LRRC17 Gene (Entity type)	-0.00751794
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB5 Gene (Entity type)	0.010100969
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MXI1 Gene (Entity type)	-0.00648742
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPX2 Gene (Entity type)	0.0071324063
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFB1 Gene (Entity type)	-0.007006624

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT2A
Gene (Entity type)
-0.007485722

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
trimetozine
Compound (Entity type)
0.2679053544998169

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD55
Gene (Entity type)
-0.0058578863

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT14
Gene (Entity type)
0.0075287786

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CEACAM5
Gene (Entity type)
0.0063072625

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LRRC17
Gene (Entity type)
-0.00751794

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINB5
Gene (Entity type)
0.010100969

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MXI1
Gene (Entity type)
-0.00648742

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPX2
Gene (Entity type)
0.0071324063

3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one (Pirenperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFB1
Gene (Entity type)
-0.007006624

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.