N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysine--tRNA ligase Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor alpha Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Activated CDC42 kinase 1 Protein (Entity type)	IC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mast/stem cell growth factor receptor Kit Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-B receptor 4 Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Vascular endothelial growth factor receptor 2 Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytoplasmic tyrosine-protein kinase BMX Protein (Entity type)	IC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fes/Fps Protein (Entity type)	IC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor beta Protein (Entity type)	EC50
N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase kinase kinase kinase 2 Protein (Entity type)	IC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysine--tRNA ligase
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor alpha
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Activated CDC42 kinase 1
Protein (Entity type)
IC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mast/stem cell growth factor receptor Kit
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-B receptor 4
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Vascular endothelial growth factor receptor 2
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytoplasmic tyrosine-protein kinase BMX
Protein (Entity type)
IC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Fes/Fps
Protein (Entity type)
IC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor beta
Protein (Entity type)
EC50

N-(3-(7-amino-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase kinase kinase kinase 2
Protein (Entity type)
IC50

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